Migraine in women:- latest research publications
"Migraine in women may be affected by hormonal changes as occur during the menstrual cycle, pregnancy, breastfeeding and use of hormonal contraceptives. Latest research on the subject is shown. A new(hopefully relevant) video chosen by google /youtube is displayed below."
Hormonal changes may affect migraines in women in various ways. Some women experience migraines around the time of menstruation (menstrual migraine), and migraines are often affected by oral contraceptive treatment. Pregnancy and
breastfeeding
are a very common time for migraines to appear or get worse. Having said this, some women note an improvement of migraines during pregnancy or experience new symptoms such as
migraine auras
. To make matters more complicated, many medications are unsuitable for pregnancy or lactation.
. It is always important to check any and all drugs or other medical treatments with a physician during pregnancy or when breast-feeding, and this includes "over-the-counter" meds.
Headaches
during pregnancy or around the time of birth are often related to
migraines
however this should not be presumed without a visit to a physician as there are other causes of "secondary-headache" which are commoner in these situations.
↑ Grab this Headline Animator
- History of childhood maltreatment isassociated with comorbid depression in women with migraine.
History of childhood maltreatment is associatedwith comorbid depression in women with migraine. Neurology. 2007 Sep 4;69(10):959-68 Authors:Tietjen GE, Brandes JL, Digre KB, Baggaley S, Martin VT, Recober A,Geweke LO, Hafeez F, Aurora SK, Herial NA, Utley C, Khuder SA BACKGROUND:A bidirectional relationship between migraine and depression suggests aneurobiological link. Adverse experiences, particularly childhoodmaltreatment, may alter neurobiological systems, and predispose to amultiplicity of adult chronic disorders. Our objective is to determine,within a headache clinic population of women, if depression moderatesthe abuse-migraine relationship. METHODS: At six headache specialtyclinics, women with migraine were diagnosed using ICHD-II criteria, andfrequency was recorded. A questionnaire regarding maltreatment history,headache characteristics, current depression, and somatic symptoms wascompleted. RESULTS: A total of 949 women with migraine completed thesurvey: 40% had chronic headache (> or =15 headache days/month)and72% had "very severe" headache-related disability. Major depression wasrecorded in 18%. Physical or sexual abuse was reported in 38%, and 12%reported both physical and sexual abuse in the past. Migraineurs withcurrent major depression reported physical (p < 0.001) andsexual (p< 0.001) abuse in higher frequencies compared to those withoutdepression. Women with major depression were more likely to reportsexual abuse occurring before age 12 years (OR = 2.30, 95% CI: 1.14 to4.77), and the relationship was stronger when abuse occurred bothbefore and after age 12 years (OR = 5.08, 95% CI: 2.15 to 11.99). Womenwith major depression were also twice as likely to report multipletypes of maltreatment (OR = 2.07, 95% CI: 1.27 to 3.35) compared tothose without depression. CONCLUSIONS: Childhood maltreatment was morecommon in women with migraine and concomitant major depression than inthose with migraine alone. The association of childhood sexual abusewith migraine and depression is amplified if abuse also occurs at alater age. migraine in women PMID : 17785661 [PubMed - indexed for MEDLINE migraine and women] 
- Association between migraine andcardiovascular disease in women.
Association between migraine and cardiovasculardisease in women. JAMA. 2006 Dec 13;296(22):2677; author reply 2677-8 migraine in women Authors: Young WB, Shaw JW migraine in women PMID : 17164448 [PubMed - indexed for MEDLINE migraine and women] 
- Incidence of migraine relative to menstrualcycle phases of rising and falling estrogen.
Incidence of migraine relative to menstrual cyclephases of rising and falling estrogen. Neurology. 2006 Dec 26;67(12):2154-8 migraine in women Authors: MacGregor EA, Frith A, Ellis J, Aspinall L,Hackshaw A OBJECTIVE:To investigate the association between urinary hormone levels andmigraine, with particular reference to rising and falling levels ofestrogen across the menstrual cycle in women with menstrual andmenstrually related migraine. METHODS: Women with regular menstrualcycles, who were not using hormonal contraception or treatments and whoexperienced between one and four migraine attacks per month, one ofwhich regularly occurred on or between days 1 +/- 2 of menstruation,were studied for three cycles. Women used a fertility monitor toidentify ovulation, conducting a test each day as requested by themonitor, using a sample of early morning urine. Urine samples werecollected daily for assay of estrone-3-glucuronide, pregnanediol3-glucuronide, follicle-stimulating hormone, and luteinizing hormone.All women kept a daily migraine diary and continued their usualtreatment for migraine. RESULTS: Of 40 women recruited, data from 38women were available for analysis. Compared with the expected number ofattacks, there was a significantly higher number of migraine attacksduring the late luteal/early follicular phase of falling estrogen andlower number of attacks during rising phases of estrogen. CONCLUSION:These findings confirm a relationship between migraine and changinglevels of estrogen, supporting the hypothesis of perimenstrual but notpostovulatory estrogen "withdrawal" migraine. In addition, risinglevels of estrogen appear to offer some protection against migraine. migraine in women PMID : 16971701 [PubMed - indexed for MEDLINE migraine and women] 
- Prevention of migraine in women throughoutthe life span.
Prevention of migraine in women throughout thelife span. Mayo Clin Proc. 2006 Aug;81(8):1086-91; quiz 1092 migraine in women Authors: Tozer BS, Boatwright EA, David PS, Verma DP,Blair JE, Mayer AP, Files JA Migraineis a common disorder in women. The 1-year prevalence of migraine is 18%in women compared with 6% in men. Migraine most commonly occurs duringthe reproductive years, affecting 27% of women 30 to 49 years of age.The predominance of this disorder and its social, functional, andeconomic consequences make migraine an important issue in women'shealth. The hormonal milieu has a substantial effect on migraine inwomen. An understanding of these hormonal influences in the variousstages of life in females is essential to the management and preventionof migraines. This article reviews migraine prevention strategies withan emphasis on specific therapies for each stage of a woman's life. migraine in women PMID : 16901031 [PubMed - indexed for MEDLINE migraine and women] 
- Migraine and risk of cardiovascular diseasein women.
Migraine and risk of cardiovascular disease inwomen. JAMA. 2006 Jul 19;296(3):283-91 migraine in women Authors: Kurth T, Gaziano JM, Cook NR, Logroscino G,Diener HC, Buring JE CONTEXT:Migraine with aura has been associated with an adverse cardiovascularrisk profile and prothrombotic factors that, along withmigraine-specific physiology, may increase the risk of vascular events.Although migraine with aura has been associated with increased risk ofischemic stroke, an association with cardiovascular disease (CVD) and,specifically, coronary events remains unclear. OBJECTIVE: To evaluatethe association between migraine with and without aura and subsequentrisk of overall and specific CVD. DESIGN, SETTING, AND PARTICIPANTS:Prospective cohort study of 27,840 US women aged 45 years or older whowere participating in the Women's Health Study, were free of CVD andangina at study entry (1992-1995), and who had information onself-reported migraine and aura status, and lipid measurements. Thisreport is based on follow-up data through March 31, 2004. MAIN OUTCOMEMEASURES: The primary outcome measure was the combined end point ofmajor CVD (first instance of nonfatal ischemic stroke, nonfatalmyocardial infarction, or death due to ischemic CVD); other measureswere first ischemic stroke, myocardial infarction, coronaryrevascularization, angina, and death due to ischemic CVD. RESULTS: Atbaseline, 5125 women (18.4%) reported any history of migraine; of the3610 with active migraine (migraine in the prior year), 1434 (39.7%)indicated aura symptoms. During a mean of 10 years of follow-up, 580major CVD events occurred. Compared with women with no migrainehistory, women who reported active migraine with aura hadmultivariable-adjusted hazard ratios of 2.15 (95% confidence interval[CI], 1.58-2.92; P<.001) for major CVD, 1.91 (95% CI, 1.17-3.10;P =.01) for ischemic stroke, 2.08 (95% CI, 1.30-3.31; P = .002) formyocardial infarction, 1.74 (95% CI, 1.23-2.46; P = .002) for coronaryrevascularization, 1.71 (95% CI, 1.16-2.53; P = .007) for angina, and2.33 (95% CI, 1.21-4.51; P = .01) for ischemic CVD death. Afteradjusting for age, there were 18 additional major CVD eventsattributable to migraine with aura per 10 000 women per year. Women whoreported active migraine without aura did not have increased risk ofany vascular events or angina. CONCLUSIONS: In this large, prospectivecohort of women, active migraine with aura was associated withincreased risk of major CVD, myocardial infarction, ischemic stroke,and death due to ischemic CVD, as well as with coronaryrevascularization and angina. Active migraine without aura was notassociated with increased risk of any CVD event. migraine in women PMID : 16849661 [PubMed - indexed for MEDLINE migraine and women] 
- The influence of estrogen on migraine: asystematic review.
The influence of estrogen on migraine: asystematic review. JAMA. 2006 Apr 19;295(15):1824-30 migraine in women Authors: Brandes JL CONTEXT:Menstrual migraine affects approximately 50% to 60% of femalemigraineurs, but knowledge regarding the role of hormones, especiallyestrogen, appears incomplete. OBJECTIVE: To conduct a systematic reviewto determine the role of hormones on menstrual migraine. EVIDENCEACQUISITION: MEDLINE migraine in women (January 1966 through September 1, 2005) andEMBASE Drugs and Pharmacology (January 1991 through September 1, 2005)were searched for articles published in the English language using thekeywords migraine, estrogen, menstrual migraine, pure menstrualmigraine, true menstrual migraine, menstrually-associated migraine,menstrually-related migraine, pregnancy, breast-feeding, perimenopause,menopause, nitric oxide, and estrogen receptors. A total of 643 uniquearticles were reviewed for relevance, scientific rigor, andgeneralizability. For each relevant citation, the bibliography wasreviewed to identify additional sources of pertinent data. EVIDENCESYNTHESIS: The influence of estrogen on migraine is evident by a 3-foldgreater prevalence among women compared with men, and by significantchanges in migraine incidence with changes in female reproductivestatus. Menstrual migraines are usually more resistant to treatment,generally not associated with aura, of longer duration, and associatedwith more functional disability compared with attacks at other times ofthe month. Biochemical and genetic evidence suggest central andperipheral roles for estrogen in the pathophysiology of menstrualmigraine, with potential interactions with excitatory circuits,including serotonergic components. Although evidence for estrogen as apreventive treatment for menstrual migraine is inconsistent, serotoninreceptor agonists (triptans) provide acute relief and also may have arole in prevention. CONCLUSIONS: Epidemiological, pathophysiological,and clinical evidence link estrogen to migraine headaches. Triptansappear to provide acute relief and also may be useful for headacheprevention. Clear, focused, and evidence-based treatment algorithms areneeded to support primary care physicians, neurologists, andgynecologists in the treatment of this common condition. migraine in women PMID : 16622141 [PubMed - indexed for MEDLINE migraine and women] 
- Clinical Inquiries.What are the besttherapies for acute migraine in pregnancy?
Clinical Inquiries.What are the best therapiesfor acute migraine in pregnancy? J Fam Pract. 2005 Nov;54(11):992-5 migraine in women Authors: Conner SJ, Rideout S, Elliott TC migraine in women PMID : 16266607 [PubMed - indexed for MEDLINE migraine and women] 
- Migraine, headache, and the risk of strokein women: a prospective study.
Migraine, headache, and the risk of stroke inwomen: a prospective study. Neurology. 2005 Mar 22;64(6):1020-6 migraine in women Authors: Kurth T, Slomke MA, Kase CS, Cook NR, Lee IM,Gaziano JM, Diener HC, Buring JE BACKGROUND:Migraine and headache in general have been associated with subsequentrisk of stroke, primarily in retrospective case-control studies.Prospective data evaluating the association between specific headacheforms and stroke are sparse. METHODS: A prospective cohort study wasconducted among 39,754 US health professionals age 45 and olderparticipating in the Women's Health Study with an average follow-up of9 years. Incident stroke was self-reported and confirmed by medicalrecord review. RESULTS: A total of 385 strokes (309 ischemic, 72hemorrhagic, and 4 undefined) occurred. Compared with nonmigraineurs,participants who reported migraine overall or migraine without aura hadno increased risk of any stroke type. Participants who reportedmigraine with aura had increased adjusted hazards ratios (HRs) of 1.53(95% CI 1.02 to 2.31) for total stroke and 1.71 (95% CI 1.11 to 2.66)for ischemic stroke but no increased risk for hemorrhagic stroke.Participants with migraine with aura who were <55 years old hada greater increase in risk of total (HR 1.75; 95% CI 1.02 to 3.00) andischemic (HR 2.25; 95% CI 1.30 to 3.91) stroke. Compared withparticipants without headache, headache in general and nonmigraineheadache were not associated with total, ischemic, or hemorrhagicstroke. CONCLUSIONS: In these prospective data, migraine was notassociated with total, ischemic, or hemorrhagic stroke. In subgroupanalyses, we found increased risks of total and ischemic stroke formigraineurs with aura. The absolute risk increase was, however, low,with 3.8 additional cases per year per 10,000 women. migraine in women PMID : 15781821 [PubMed - indexed for MEDLINE migraine and women] 
- Migraine in special populations. Treatmentstrategies for children and adolescents, pregnant women, and theelderly.
Migraine in special populations. Treatmentstrategies for children and adolescents, pregnant women, and theelderly. Postgrad Med. 2004 Apr;115(4):39-44, 47-50 migraine in women Authors: Gladstone JP, Eross EJ, Dodick DW Althoughmigraine is a common occurrence in children and adolescents, itsdiagnosis and treatment present unique challenges. Migraine managementin pregnant women and the elderly can also be difficult and requiresselection of appropriate and safe medications for patients in thesespecial circumstances. In this article, Drs Gladstone, Eross, andDodick provide pearls for both abortive and prophylactic treatments formigraine in these populations. migraine in women PMID : 15095531 [PubMed - indexed for MEDLINE migraine and women] 
- Linking olfaction with nausea and vomitingof pregnancy, recurrent abortion, hyperemesis gravidarum, and migraineheadache.
Linking olfaction with nausea and vomiting ofpregnancy, recurrent abortion, hyperemesis gravidarum, and migraineheadache. Am J Obstet Gynecol. 2002 May;186(5 SupplUnderstanding):S215-9 migraine in women Authors: Heinrichs L OBJECTIVE:The experience of women was sought about nausea and vomiting, itsrelation to olfaction, its occurrence among pregnant women withanosmia, and the potential association of hyperemesis gravidarum andmigraine headache. METHODS: We performed a community-based study with aphysician/patient-directed questionnaire, and a retrospective analysisof hospital records. RESULTS: Nearly all women (n = 163 parous women)experience nausea (98%) and vomiting (97%). The highest frequencycauses of nausea and vomiting were "food poisoning" (65%), "flu" (58%),pregnancy (54%), and offensive odors (52%); vomiting occurred asfrequently as nausea for the first 2 causes, and one half as often forthe latter causes. Most women reported that the pain experienced duringvomiting exceeded that of parturition. Among 9 women withhypogonadotropic anosmia with advanced reproductive technology-inducedpregnancies, 2 experienced nausea and vomiting, one from "foodpoisoning." Among 37 women with migraine headache, 10 (27%) hadexperienced hyperemesis gravidarum, and among 16 who experiencedhyperemesis gravidarum, 5 (37%) had migraine headaches. CONCLUSIONS:The frequency of nausea and vomiting, caused most often bynonpregnancy-related triggers, is high among women. In a small sampleof women with congenital anosmia, nausea and vomiting of pregnancyoccurred in only 1 pregnancy, suggesting that olfaction is a highlyselected trigger for nausea and vomiting of pregnancy. The sharednausea and vomiting experience of hyperemesis gravidarum and migraineheadache among women suggests a common mechanism, possibly based onallelic variations within the DRD2 (dopaminergic receptor) gene.Because olfactory receptors, odor types, and MHC antigens are closelyintegrated, and because olfactory stimuli often incite episodes ofpregnancy, nausea, and vomiting, hyperemesis gravidarum, and migraineheadache, these genes and their products invite further scrutiny. Thepregnancy-conserving effect of PNV and the MHC antigen overlap incouples with recurrent abortion are important clues possibly relatingolfaction, MHC antigens, and reproductive success or failure. migraine in women PMID : 12011889 [PubMed - indexed for MEDLINE migraine in women] 
- Migraine in pregnancy.
Migraine in pregnancy. Neurology. 1999;53(4 Suppl 1):S26-8 migraine in women Authors: Aubé M Migrainedoes not increase the risk for complications of pregnancy for themother or for the fetus: the incidences of toxemia, miscarriages,abnormal labour, congenital anomalies, and stillbirths are comparableto those of the general population. Several retrospective studies haveshown a tendency for migraine to improve with pregnancy. Between 60 and70% of women either go into remission or improve significantly, mainlyduring the second and third trimesters. Women with migraine onset atmenarche and those with perimenstrual migraine are more likely to gointo remission during pregnancy. The migraine type does not seem to bea significant prognostic factor for improvement. However, in the smallnumber of women (4-8%) whose migraines worsen with pregnancy, migrainewith aura appears to be overrepresented. In a small number of cases(1.3-16.5%), migraine appears to start with pregnancy, often in thefirst trimester; these headaches involve a higher proportion ofmigraine with aura. Management of migraine during pregnancy shouldfirst focus on avoiding potential triggers. Consideration should alsobe given to nonpharmacologic therapies. If pharmacologic treatmentbecomes necessary, acetaminophen and codeine can be used safely asabortive agents; ASA and NSAIDs (ibuprofen, naproxen) can be used as asecond choice, but not for long periods of time, and they should beavoided during the last trimester. For treatment of severe attacks ofmigraine, chlorpromazine, dimenhydrinate, and diphenhydramine can beused; metoclopramide should be restricted to the third trimester.According to the United States FDA risk categories, meperidine andmorphine show no evidence of risk in humans but should not be used atthe end of the third trimester. In some refractory cases, dexamethasoneor prednisone can be considered. Should prophylactic treatment becomeindicated, the beta-adrenergic receptor antagonists (e.g., propranolol)can be used. migraine in women PMID : 10487511 [PubMed - indexed for MEDLINE migraine and women] 
- Migraine and stroke in young women.Prospective study is needed to determine what clinical practice inmigraine should be.
Migraine and stroke in young women. Prospectivestudy is needed to determine what clinical practice in migraine shouldbe. BMJ. 1999 May 29;318(7196):1485-6 migraine in women Authors: Olesen J migraine in women PMID : 10419299 [PubMed - indexed for MEDLINE migraine in women] 
- Migraineand stroke in young women. Authors' results suggest that all types ofmigraine are contraindications to oral contraceptives.
Migraineand stroke in young women. Authors' results suggest that all types ofmigraine are contraindications to oral contraceptives. BMJ. 1999 May 29;318(7196):1485; author reply 1486 migraine in women Authors: MacGregor EA, Guillebaud J migraine in women PMID : 10346781 [PubMed - indexed for MEDLINE migraine and women] 
- Migraineand stroke in young women: case-control study. The World HealthOrganisation Collaborative Study of Cardiovascular Disease and SteroidHormone Contraception.
Migraineand stroke in young women: case-control study. The World HealthOrganisation Collaborative Study of Cardiovascular Disease and SteroidHormone Contraception. BMJ. 1999 Jan 2;318(7175):13-8 migraine in women Authors: Chang CL, Donaghy M, Poulter N OBJECTIVE:To investigate the association between migraine and ischaemic orhaemorrhagic stroke in young women. DESIGN: Hospital based case-controlstudy. SETTING: Five European centres participating in the World HealthOrganisation Collaborative Study of Cardiovascular Disease and SteroidHormone Contraception. SUBJECTS: 291 women aged 20-44 years withischaemic, haemorrhagic, or unclassified arterial stroke compared with736 age and hospital matched controls. INTERVENTION: Questionnaire.MAIN OUTCOME MEASURE: Self reported history of headaches. RESULTS:Adjusted odds ratios associated with a personal history of migrainewere 1.78 (95% confidence intervals, 1.14 to 2.77), 3.54 (1.30 to9.61), and 1.10 (0.63 to 1.94) for all stroke, ischaemic stroke, andhaemorrhagic stroke respectively. Odds ratios for ischaemic stroke weresimilar for classical migraine (with aura) (3.81, 1.26 to 11.5) andsimple migraine (without aura) (2.97, 0.66 to 13.5). A family historyof migraine, irrespective of personal history, was also associated withincreased odds ratios, not only for ischaemic stroke but alsohaemorrhagic stroke. In migrainous women, coexistent use of oralcontraceptives or a history of high blood pressure or smoking hadgreater than multiplicative effects on the odds ratios for ischaemicstroke associated with migraine alone. Change in the frequency or typeof migraine on using oral contraceptives did not predict subsequentstroke. Between 20% and 40% of strokes in women with migraine seemed todevelop directly from a migraine attack. CONCLUSIONS: Migraine in womenof childbearing age significantly increases the risk of ischaemic butnot haemorrhagic stroke. The coexistence of oral contraceptive use,high blood pressure, or smoking seems to exert a greater thanmultiplicative effect on the risk of ischaemic stroke associated withmigraine. migraine in women PMID : 9872871 [PubMed - indexed for MEDLINE migraine and women] 
- Oralcontraceptives, pregnancy and the risk of cerebral thromboembolism: theinfluence of diabetes, hypertension, migraine and previous thromboticdisease.
Oralcontraceptives, pregnancy and the risk of cerebral thromboembolism: theinfluence of diabetes, hypertension, migraine and previous thromboticdisease. Br J Obstet Gynaecol. 1996 Jan;103(1):93-4 migraine in women Authors: Schwingl PJ migraine in women PMID : 8608111 [PubMed - indexed for MEDLINE migraine and women] 
- Migraine and women. The link betweenheadache and hormones.
Migraine and women. The link between headache andhormones. Postgrad Med. 1995 Apr;97(4):147-53 migraine in women Authors: Silberstein SD Levelsof sex hormones fluctuate throughout the female life cycle, and thesefluctuations may trigger, intensify, or alleviate migraine. Drugs canbe used both preventively and therapeutically to combat the headachethat results in some women from such fluctuations. Effectiveprophylactic agents include beta blockers, antidepressants, calciumchannel blockers, and hormones. Nonsteroidal anti-inflammatory drugs,ergotamine and its derivatives, and narcotics are among the abortivetherapy options. Pharmacologic management of migraine in pregnant womenmust be conservative because of the risks of injury and dependence tothe fetus and newborn. migraine in women PMID : 7716087 [PubMed - indexed for MEDLINE migraine and women] 
- Case-control study of migraine and risk ofischaemic stroke in young women.
Case-control study of migraine and risk ofischaemic stroke in young women. BMJ. 1995 Apr 1;310(6983):830-3 migraine in women Authors: Tzourio C, Tehindrazanarivelo A,Iglésias S, Alpérovitch A, Chedru F,d'Anglejan-Chatillon J, Bousser MG OBJECTIVE--Todetermine whether migraine is a risk factor for ischaemic stroke inyoung women. DESIGN--A case-control study. SETTING--Five hospitals inParis and suburbs. SUBJECTS--72 women aged under 45 with ischaemicstroke and 173 controls randomly selected from women hospitalised inthe same centres. MAIN OUTCOME MEASURES--Ischaemic stroke confirmed bycerebral computerised tomography or magnetic resonance imaging; historyof headache recorded with structured interview, and diagnosis ofmigraine assessed by reproducibility study. RESULTS--Ischaemic strokewas strongly associated with migraine, both migraine without aura (oddsratio 3.0 (95% confidence interval 1.5 to 5.8)) and migraine with aura(odds ratio 6.2 (2.1 to 18.0)). The risk of ischaemic stroke wassubstantially increased for migrainous women who were using oralcontraceptives (odds ratio 13.9) or who were heavy smokers (> or= 20 cigarettes/day) (odds ratio 10.2). CONCLUSIONS--These resultsindicate an independent association between migraine and the risk ofischaemic stroke in young women. Although the absolute risk ofischaemic stroke in young women with migraine is low, the reduction ofknown risk factors for stroke, in particular smoking and use of oralcontraceptives, should be considered in this group. migraine in women PMID : 7711619 [PubMed - indexed for MEDLINE migraine in women] 
- Oralcontraceptives, pregnancy and the risk of cerebral thromboembolism: theinfluence of diabetes, hypertension, migraine and previous thromboticdisease.
Oralcontraceptives, pregnancy and the risk of cerebral thromboembolism: theinfluence of diabetes, hypertension, migraine and previous thromboticdisease. Br J Obstet Gynaecol. 1995 Feb;102(2):153-9 migraine in women Authors: Lidegaard O OBJECTIVE:To assess the risk of developing cerebral thromboembolism amongpregnant women and among fertile women with hypertension, migraine,diabetes, and previous thrombotic disease, and to investigate theinteraction of these risk factors with the use of oral contraceptives.DESIGN: A retrospective case-control study. SETTING: Allgynaecological, medical, neurological, and neurosurgical departments inDanish hospitals. SUBJECTS: Seven hundred and ninety-four women inDenmark aged 15 to 44 who suffered a cerebral thromboembolic attackduring the period 1985 to 1989 and 1588 age-matched, randomly selectedcontrols. RESPONSE: Of the 692 case and 1584 control questionnairessent out, 590 (85.1%) and 1396 (88.1%), respectively, were returned. Ofthe 590 cases, nine had had cerebral thrombosis before 1980, 15 refusedto participate, 44 had a revised diagnosis (primarily multiplesclerosis) and 25 had an unreliable diagnosis, leaving 497 with areliable cerebral thromboembolic diagnosis. Among the 1396 controls, 26either refused to participate, were mentally handicapped, lived abroador returned an uncompleted questionnaire, leaving 1370 controlsincluded in the study. RESULTS: After multivariate analysis, pregnancyimplied an odds ratio (OR) for a cerebral thromboembolic attack of 1.3(nonsignificant), diabetes an OR of 5.4 (P < 0.001),hypertension anOR of 3.1 (P < 0.001) and migraine an OR of 2.8 (P <0.01). Womenwith previous non-cerebral thrombotic disease had an OR for cerebralthrombo-embolism of 5.3 (P < 0.001). Women with otherpredisposingmedical diseases had an OR of 8.3 (P < 0.001). These ORs wereidentical among users and non-users of combined oral contraceptives.CONCLUSION: In this study pregnancy implied a non-significant elevatedodds ratio of 1.3 for cerebral thromboembolism whereas diabetes,hypertension, migraine and past thromboembolic events increased therisk of cerebral thromboembolism significantly. Women with theseincreased thrombotic risks should use oestrogen-containing oralcontraceptives only after careful considerations of the risks, if atall. migraine in women PMID : 7756208 [PubMed - indexed for MEDLINE migraine and women] 
- Aspirin and migraine: what about women?
Aspirin and migraine: what about women? JAMA. 1991 Jan 23-30;265(4):461 migraine in women Authors: Akama H, Tsuji S migraine in women PMID : 1985231 [PubMed - indexed for MEDLINE migraine and women] 
- Asthma and eczema in children born to womenwith migraine.
Asthma and eczema in children born to women withmigraine. Arch Neurol. 1990 Nov;47(11):1227-30 migraine in women Authors: Chen TC, Leviton A Migraineand asthma have been reported to occur in the same person more commonlythan would be expected if they are independent. The large CollaborativePerinatal Project provided an opportunity to see if children born towomen with migraine or with the group of disorders characterized byasthma and/or allergies were more likely to manifest asthma or eczemain the first 7 years of life. Among children whose mothers had neithermigraine nor asthma/allergies, 3.2% had asthma. Of children whosemothers had migraine, but not asthma/allergies, more than 6% hadasthma. The risk of asthma among children born to women who had bothmigraine and asthma/allergies was greater than the risk associated witheach maternal disease. The risk of eczema in children was notappreciably influenced by the mother's propensity to migraine orasthma/allergies. The results of this first study of migraine in onegeneration and asthma in the next lead to the conclusion that the twodisorders are probably related. migraine in women PMID : 2241619 [PubMed - indexed for MEDLINE migraine in women] 
- Basilar migraine with loss of consciousnessin pregnancy. Case report.
Basilar migraine with loss of consciousness inpregnancy. Case report. Br J Obstet Gynaecol. 1989 Apr;96(4):494-5 migraine in women Authors: Jacobson SL, Redman CW migraine in women PMID : 2751961 [PubMed - indexed for MEDLINE migraine and women] 
- Migraine and other diseases in women ofreproductive age. The influence of smoking on observed associations.
Migraine and other diseases in women ofreproductive age. The influence of smoking on observed associations. Arch Neurol. 1987 Oct;44(10):1024-8 migraine in women Authors: Chen TC, Leviton A, Edelstein S, Ellenberg JH Fromamong the pregnant women in the Collaborative Perinatal Project of theNational Institute of Neurological and Communicative Disorders andStroke, we identified 508 who had migraine, and 3192 who had no historyof migraine, of taking headache medication during the previous 12months, and of headaches during the pregnancy. Migraineurs smoked moreheavily and had a longer smoking history than their headache-freepeers. Among migraineurs, smokers were not more likely to consumeanalgesics than nonsmokers. Regardless of smoking classification, moremigraineurs consumed tranquilizers, amphetamines, and sleeping pillsthan headache-free women. Among smokers only, migraine was associatedwith heart disease, thrombosis/phlebitis, asthma, peptic ulcer, andpneumonia. In nonsmokers, migraine was associated with drug sensitivityand other allergies. migraine in women PMID : 3632371 [PubMed - indexed for MEDLINE migraine and women] 
- Focal migraine and pregnancy.
Focal migraine and pregnancy. Br Med J (Clin Res Ed). 1986 Dec 13;293(6561):1557-8 migraine in women Authors: Wright GD, Patel MK migraine in women PMID : 3099951 [PubMed - indexed for MEDLINE migraine and women] 
- Migraine, headache, and survival in women.
Migraine, headache, and survival in women. Br Med J (Clin Res Ed). 1984 Jan 7;288(6410):67-8 migraine in women Authors: migraine in women PMID : 6418321 [PubMed - indexed for MEDLINE migraine and women] 
- Migraine, headache, and survival in women.
Migraine, headache, and survival in women. Br Med J (Clin Res Ed). 1983 Dec 3;287(6406):1718 migraine in women Authors: Grant EC migraine in women PMID : 6416558 [PubMed - indexed for MEDLINE migraine and women] 
- Migraine, headache, and survival in women.
Migraine, headache, and survival in women. Br Med J (Clin Res Ed). 1983 Nov 12;287(6403):1442-3 Authors: Waters WE, Campbell MJ, Elwood PC Apopulation study of 1310 women aged 45-64 years determined theprevalence of headache and migraine in the preceding year. Toinvestigate the hypothesis that women with migraine had a highermortality rate, these women were followed up nearly 12 years later.Unexpectedly, the mortality was found to be higher in women withoutheadaches. Women with headaches and migraine had a relative risk ofdying of 0.72 (95% confidence interval 0.52-1.00) compared with thosewithout headaches. PMID: 6416449 [PubMed - indexed for MEDLINE migraine in women] 
- Linksfor 2007-12-19 [del.icio.us]
- Linksfor 2007-12-17 [del.icio.us]
Find something specific
Ask a question regarding migraine in women
Navigate to main headache page
|
