MRI in MS:- Can a brain MRI be normal in MS?

MRI in MS:- Can a brain MRI be normal in MS?;(Melodi)

Is it possible to have multiple sclerosis and it not show up on an MRI?

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  • asktheneurologist

    The simple answer to this question is yes…..but........

    I would very much like to know why the MRI was performed:-in otherwords what were the symptoms / clinical signs leading to the test beingordered?

    Multiple Sclerosis (MS) has strict criteria for diagnosis.The mostcommonly used criteria are known as the “Mc DonaldCriteria” which werepublished in the journal “Annals of Neurology” in2001 (Ann Neurol2001;50:121–127).

    A table summarizing these criteria can be viewed here:-

    In some cases of MS the brain MRI can be normal althoughthis is not a common occurrence.

    In fact the diagnosis of MS can still be made withoutperforming anMRI, although this is rarely the situation in situations where MRIscanning is readily available.

    MSExpert 2

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